Projector - a partially typed language for querying XML

We describe Projector, a language that can be used to perform a mixture of typed and untyped computation against data represented in XML. For some problems, notably when the data is unstructured or semistructured, the most desirable programming model is against the tree structure underlying the document. When this tree structure has been used to model regular data structures, then these regular structures themselves are a more desirable programming model. The language Projector, described here in outline, gives both models within a single partially typed algebra and is well suited for hybrid applications, for example when fragments of a known structure are embedded in a document whose overall structure is unknown. Projector is an extension of ECMA-262 (aka JavaScript), and therefore inherits an untyped DOM interface. To this has been added some static typing and a dynamic projection primitive, which can be used to assert the presence of a regular structure modelled within the XML. If this structure does exist, the data is extracted and presented as a typed value within the programming language

The case for metadata harvesting

Metadata harvesting is an increasingly popular model of interaction between the mutually autonomous parties of medium, medium-large federations of digital library services. With a harvesting protocol, in particular, resource descriptions locally available at each party can be served to remote applications for the implementation of federated services, such as resource discovery. This article offers a systematic explanation of the success of the model and its standard implementations in the context of current initiatives for national and international federations

From research data repositories to virtual research environments: a case study from the Humanities

The difference in scholarly practices between the sciences and the mainstream humanities is highlighted in a study (Palmer et al., 2009), which investigated the types of information source materials used in different humanities disciplines, based on results contained in the US Research Libraries Group (RLG) reports. Structured data is relatively little used, except in some areas of historical research, and data as it is traditionally understood in the sciences, i.e. the results of measurements and the lowest level of abstraction for the generation of scientific knowledge, even less so. It is true that the study is partly outdated, containing results from the early 1990s, and that data in the traditional sense is becoming increasingly important in the humanities, particularly for disciplines such as linguistics and archaeology in which scientific techniques have been widely adopted. Nevertheless, it is clear that in general humanities research relies not on measurements as a source of authority, but rather on the provenance of sources and assessment by peers, and that what data repositories are for the sciences, archives are for the humanities. [...

From research data repositories to virtual research environments: a case study from the Humanities

The difference in scholarly practices between the sciences and the mainstream humanities is highlighted in a study (Palmer et al., 2009), which investigated the types of information source materials used in different humanities disciplines, based on results contained in the US Research Libraries Group (RLG) reports. Structured data is relatively little used, except in some areas of historical research, and data as it is traditionally understood in the sciences, i.e. the results of measurements and the lowest level of abstraction for the generation of scientific knowledge, even less so. It is true that the study is partly outdated, containing results from the early 1990s, and that data in the traditional sense is becoming increasingly important in the humanities, particularly for disciplines such as linguistics and archaeology in which scientific techniques have been widely adopted. Nevertheless, it is clear that in general humanities research relies not on measurements as a source of authority, but rather on the provenance of sources and assessment by peers, and that what data repositories are for the sciences, archives are for the humanities. [...

Data for the analysis of willingness to pay for Italian beaches

The data presented herein relates to the article entitled \u201cWillingness to pay for management and preservation of natural, semi-urban and urban beaches in Italy\u201d [1]. Data of several Italian beaches are collected considering shape, anthropogenic characteristics, use, activity and urbanization levels. Descriptive statistics of beach characteristics and beach users are presented, on the basis of about 5,000 interviews

Verification of the electromagnetic deep-penetration effect in the real world

The deep penetration of electromagnetic waves into lossy media can be obtained by properly generating inhomogeneous waves. In this work, for the very first time, we demonstrate the physical implementation and the practical relevance of this phenomenon. A thorough numerical investigation of the deep-penetration effects has been performed by designing and comparing three distinct practical radiators, emitting either homogeneous or inhomogeneous waves. As concerns the latter kind, a typical Menzel microstrip antenna is first used to radiate improper leaky waves. Then, a completely new approach based on an optimized 3-D horn TEM antenna applied to a lossy prism is described, which may find applications even at optical frequencies. The effectiveness of the proposed radiators is measured using different algorithms to consider distinct aspects of the propagation in lossy media. We finally demonstrate that the deep penetration is possible, by extending the ideal and theoretical evidence to practical relevance, and discuss both achievements and limits obtained through numerical simulations on the designed antennas

Older tourists' travel motivations and overall satisfaction at the destination: The case of Sirmione

Purpose: As the number of older tourists is progressively growing due to population ageing, tourism destinations are increasingly striving to attract them. For this purpose, destination marketers need to gain deep knowledge about the relationships between older tourists\u2019 travel motivations and satisfaction at the destination. This paper aims to provide an in-depth examination of such relationships in a specific destination, highlighting the effects of four travel motivations (culture; pleasure-seeking; relaxation; physical). Methodology: A cross-section design was adopted based on a survey among a sample of older tourists visiting Sirmione, a mature destination located on Lake Garda, Italy. Data were analyzed through multiple techniques, including analyses of variance and linear regression. Findings: The results reveal that relaxation was the most important motivation making older tourists decide to visit Sirmione. Moreover, relaxation was the only motivation showing a statistically significant relationship with satisfaction at the destination. Practical implications: The results of this study provide destination managers with valuable inputs to reposition their destination to effectively attract older tourists. Originality/value: This paper contributes to enhance available knowledge \u2013 which is quite scarce \u2013 about the effects of travel motivations on satisfaction at the destination among older tourists

Lattice Boltzmann method for warm fluid simulations of plasma wakefield acceleration

A comprehensive characterization of lattice Boltzmann (LB) schemes to perform warm fluid numerical simulations of particle wakefield acceleration (PWFA) processes is discussed in this paper. The LB schemes we develop hinge on the moment matching procedure, allowing the fluid description of a warm relativistic plasma wake generated by a driver pulse propagating in a neutral plasma. We focus on fluid models equations resulting from two popular closure assumptions of the relativistic kinetic equations, i.e., the local equilibrium and the warm plasma closure assumptions. The developed LB schemes can thus be used to disclose insights on the quantitative differences between the two closure approaches in the dynamics of PWFA processes. Comparisons between the proposed schemes and available analytical results are extensively addressed.Comment: 8 figure

SOGS-RA gambling scores and substance use in adolescents

Background and aims There is a well-established association between pathological gambling and substance use disorders in adolescents. The aim of this study was to shed light on the association between adolescents’ different levels of involvement in gambling activities and substance use (smoking tobacco and cannabis and drinking alcoholic beverages), based on a large sample. Methods A survey was conducted in 2013 on 34,746 students attending 619 secondary schools, who formed a representative sample of the Italian 15- to 19-year-old population. The prevalence of different categories of gamblers was estimated by age group and gender. A multiple correspondence analysis (CA) was conducted to explain the multivariate associations between substance use and gambling. Results The prevalence of problem gambling was 2.7% among the 15- to 17-year-olds, and rose to 3.6% among the 18- and 19-year-olds. Multiple CA revealed that, even when it does not reach risk-related or problem levels, gambling is associated with the use of alcohol and tobacco. In particular, the analysis showed that non-problem gambling levels were associated with alcohol and tobacco use at least once in the previous month, and that higher-risk gambling levels related to the use of cannabis and episodes of drunkenness at least once in the previous month. Conclusion This study found that any gambling behavior, even below risk-related or problem levels, was associated with some degree of substance use by youths, and that adolescents’ levels of gambling lay along a continuum of the categories of substance use

HMG20B stabilizes association of LSD1 with GFI1 on chromatin to confer transcription repression and leukemia cell differentiation block

Pharmacologic inhibition of LSD1 induces molecular and morphologic differentiation of blast cells in acute myeloid leukemia (AML) patients harboring MLL gene translocations. In addition to its demethylase activity, LSD1 has a critical scaffolding function at genomic sites occupied by the SNAG domain transcription repressor GFI1. Importantly, inhibitors block both enzymatic and scaffolding activities, in the latter case by disrupting the protein:protein interaction of GFI1 with LSD1. To explore the wider consequences of LSD1 inhibition on the LSD1 protein complex we applied mass spectrometry technologies. We discovered that the interaction of the HMG-box protein HMG20B with LSD1 was also disrupted by LSD1 inhibition. Downstream investigations revealed that HMG20B is co-located on chromatin with GFI1 and LSD1 genome-wide; the strongest HMG20B binding co-locates with the strongest GFI1 and LSD1 binding. Functional assays demonstrated that HMG20B depletion induces leukemia cell differentiation and further revealed that HMG20B is required for the transcription repressor activity of GFI1 through stabilizing LSD1 on chromatin at GFI1 binding sites. Interaction of HMG20B with LSD1 is through its coiled-coil domain. Thus, HMG20B is a critical component of the GFI1:LSD1 transcription repressor complex which contributes to leukemia cell differentiation block